Ménière's Disease: Current and Potential New Objective Measures Using Electrocochleography The characteristic manifestations of Ménière's disease (MD) are mainly subjective, making MD difficult for physicians to diagnose without objective confirmation. A classic electrophysiologic technique for objective diagnosis of MD is electrocochleography (ECochG) to slow stimulus rates. This review will provide information regarding the sensitivity, specificity, and limitations of the conventional ... Article
Article  |   November 01, 2015
Ménière's Disease: Current and Potential New Objective Measures Using Electrocochleography
Author Affiliations & Notes
  • Wafaa A. Kaf
    Communication Sciences and Disorders Department, Missouri State University, Springfield, MO
  • Mohamed K. Abdelhakiem
    Medical School, Medical College of Wisconsin, Milwaukee, WI
  • Zisansha Zahirsha
    Biology Department, Saint Louis University, Saint Louis, MO
  • Jeffery T. Lichtenhan
    Department of Otolaryngology, Washington University School of Medicine, Saint Louis, MO
  • Financial Disclosure: Wafaa A. Kaf is a professor at Missouri State University. Mohamed K. Abdelhakiem is a medical student at the Medical College of Wisconsin. Zisansha Zahirsha is a student at Saint Louis University. Jeffery T. Lichtenhan is an assistant professor at Washington University School of Medicine in St. Louis.
    Financial Disclosure: Wafaa A. Kaf is a professor at Missouri State University. Mohamed K. Abdelhakiem is a medical student at the Medical College of Wisconsin. Zisansha Zahirsha is a student at Saint Louis University. Jeffery T. Lichtenhan is an assistant professor at Washington University School of Medicine in St. Louis.×
  • Nonfinancial Disclosure: Wafaa A. Kaf and Jeffery T. Lichtenhan have previously published in the subject area. Mohamed K. Abdelhakiem and Zisansha Zahirsha have no nonfinancial interests related to the content of this article. Some of the ECochG data using CLAD from this manuscript have been presented at the MARC-MANS meeting (2014) and the American Auditory Society meeting (2015). Portions of this work was supported by grants from the Hearing Health Foundation (W.K.) and the National Institutes of Health, National Institute on Deafness and Other Communication Disorders (R03 DC012844 to J.T.L.).
    Nonfinancial Disclosure: Wafaa A. Kaf and Jeffery T. Lichtenhan have previously published in the subject area. Mohamed K. Abdelhakiem and Zisansha Zahirsha have no nonfinancial interests related to the content of this article. Some of the ECochG data using CLAD from this manuscript have been presented at the MARC-MANS meeting (2014) and the American Auditory Society meeting (2015). Portions of this work was supported by grants from the Hearing Health Foundation (W.K.) and the National Institutes of Health, National Institute on Deafness and Other Communication Disorders (R03 DC012844 to J.T.L.).×
Article Information
Hearing Disorders / Balance & Balance Disorders / Articles
Article   |   November 01, 2015
Ménière's Disease: Current and Potential New Objective Measures Using Electrocochleography
SIG 6 Perspectives on Hearing and Hearing Disorders: Research and Diagnostics, November 2015, Vol. 19, 44-54. doi:10.1044/hhd19.2.44
History: Received July 21, 2015 , Revised September 6, 2015 , Accepted September 22, 2015
SIG 6 Perspectives on Hearing and Hearing Disorders: Research and Diagnostics, November 2015, Vol. 19, 44-54. doi:10.1044/hhd19.2.44
History: Received July 21, 2015; Revised September 6, 2015; Accepted September 22, 2015

The characteristic manifestations of Ménière's disease (MD) are mainly subjective, making MD difficult for physicians to diagnose without objective confirmation. A classic electrophysiologic technique for objective diagnosis of MD is electrocochleography (ECochG) to slow stimulus rates. This review will provide information regarding the sensitivity, specificity, and limitations of the conventional click and frequency specific ECochG measures. In addition, the paper will discuss two novel, promising techniques: fast click ECochG with the use of continuous loop averaging deconvolution (CLAD) and the auditory nerve overlapped waveform (ANOW). These new techniques may offer a new way in diagnosing MD through assessing neural adaptation and function of the apical half of the cochlear spiral.

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